Дополнительная информация

Hb взрослого организма состоит, как упомянуто выше, из двух α- и двух β-цепей (α2β2). Наряду с этой основной формой (HbA1) в крови присутствуют незначительные количества второй формы с более высоким сродством к O2, у которой β-цепи заменены δ-цепями (HbA2, α2δ2).

Две другие формы Hb встречаются только в эмбриональном периоде развития. В первые три месяца образуются эмбриональные гемоглобины состава ξ2ε2 и α2γ2. Затем вплоть до рождения доминирует фетальный гемоглобин (HbF, α2δ2). который постепенно заменяется на первом месяце жизни на HbA. Эмбриональный и фетальный гемоглобины обладают более высоким сродством к O2 по сравнению с HbA, так как они должны переносить кислород из системы материнского кровообращения.


Ткани и органы. Кровь / Гемоглобин

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