Б. Полисома

Клетки, в которых происходит активный синтез белков, часто содержат рибосомы, расположенные одна за другой подобно жемчужинам на нитке, в виде так называемой полисомы. Это объясняется тем, что одна молекула мРНК может транслироваться одновременно несколькими рибосомами. Первой стадией трансляции является связывание рибосомы со стартовым (инициирующим) кодоном (AUG, см. Генетический код, активация аминокислот) вблизи 5′-конца мРНК. По мере трансляции рибосома движется по направлению к 3′-концу до тех пор, пока не дойдёт до терминирующего кодона (стоп-кодона) (UAA, UAG или UGA). Как только рибосома достигает стоп-кодона, происходит освобождение синтезированного белка и диссоциация рибосомы на отдельные субчастицы.


Молекулярная генетика / Рибосомы: инициация трансляции

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