Класс 6: Лигазы (соединяют две молекулы при гидролизе макроэргических связей)

Подклассы 6.n: Зависят от природы образующейся связи

6.1Образуют связи C-O
6.1.1.n(Аминокислота)-тРНК-лигазы («аминоацил-тРНК-синтетазы»)
6.2Образуют связи C-S
6.2.1.1Ацетат-СоА-лигаза
6.2.1.3Длинноцепочечная жирная кислота-СоА-лигаза
6.2.1.4Сукцинат-СоА-лигаза (образующая GDP) — «тиокиназа»
6.3Образуют связи C-N
6.3.1.2Глутамат-NH3-лигаза — «глутаминсинтетаза»
6.3.2.6Фосфорибозиламиноимидазолсукцинокарбоксамид-синтаза
6.3.3.1Фосфорибозилформилглицинамидин-цикполигаза
6.3.3.25-Формилтетрагидрофолат-циклолигаза
6.3.4.2СТР-синтаза
6.3.4.4Аденилосукцинат-синтаза
6.3.4.5Аргининосукцинат-синтаза
6.3.4.13Фосфорибозиламинглицин-лигаза
6.3.4.16Карбамоилфосфат-синтаза (NH3)
6.3.5.2GMP-синтаза (гидролизующая глутамин)
6.3.5.3Фосфорибозилформилглицинамидин-синтаза
6.3.5.4Аспарагин-синтаза (гидролизующая глутамин)
6.3.5.5Карбамоилфосфат-синтаза (гидролизующая глутамин)
6.4Образуют связи C-C
6.4.1.1Пируваткарбоксилаза [биотин]
6.4.1.2Ацетил-СоА-карбоксилаза [биотин]
6.4.1.3Пропионил-СоА-карбоксилаза[биотин]
6.4.1.4Метилкротонил-СоА-карбоксилаза [биотин]
6.5Образуют связи P-O
6.5.1.1ДНК-лигаза (АТР)

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