Клонирование ДНК

Развитие молекулярной генетики с 70-х гг. в значительной степени основано на разработке и совершенствовании методов анализа и манипулирования ДНК. Так называемая «генная (генетическая) инженерия» имеет практические приложения во многих областях. Например, были разработаны новые методы диагностики и лечения заболеваний и стало возможным проводить направленные изменения определённых свойств организма. Поскольку полностью исключить биологический риск невозможно, при использовании методов генной инженерии необходим осторожный подход. В этом и последующих разделах дан краткий обзор методов, используемых в генной инженерии.


Молекулярная генетика. Генная инженерия / Клонирование ДНК

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Role of TCF in body axis formation: Discovery of a Dual Action of XTCF-3 in Xenopus Body Axis Formation / A novel role of TCF family in body axis formation. Revolutionary high impact discoveries are described, elucidating the missing link in the Wnt pathway and protein-TCF combinations with dual functions. By studying the primary axis formation of Xenopus laevis, it was firstly shown that, in combinatioRole of TCF in body axis formation: Discovery of a Dual Action of XTCF-3 in Xenopus Body Axis Formation
A novel role of TCF family in body axis formation. Revolutionary high impact discoveries are described, elucidating the missing link in the Wnt ...
Histone H1 glycation and rutin metabolites as glycation inhibitors: Nuclear protein glycation in vivo and novel natural product AGE inhibitors / Protein glycation, induced by hyperglycemia, is implicated in the appearance of diabetic complications and the aging process. Glycation involves the non-enzymatic reaction between sugars and protein amino groups that lead to formation of advanced glycation end products (AGEs). When aminoguanidine, aHistone H1 glycation and rutin metabolites as glycation inhibitors: Nuclear protein glycation in vivo and novel natural product AGE inhibitors
Protein glycation, induced by hyperglycemia, is implicated in the appearance of diabetic complications and the aging process. Glycation involves the ...
Metals in Medicine / Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss important bonding concepts applicable to metallo-drugs and their biological targets, interactions that exist between the agents and substances in the bioMetals in Medicine
Working from basic chemical principles, Metals in Medicine presents a complete and methodical approach to the topic. Introductory chapters discuss ...
Yeast: Molecular and Cell Biology / Yeast is one of the oldest domesticated organisms and has both industrial and domestic applications. In addition, it is very widely used as a eukaryotic model organism in biological research and has offered valuable knowledge of genetics and basic cellular processes. In fact, studies in yeast have oYeast: Molecular and Cell Biology
Yeast is one of the oldest domesticated organisms and has both industrial and domestic applications. In addition, it is very widely used as a ...